📋 Tender Overview
Plasmodium Liver Stage Schizogony: High Replication And Genetic Diversity
Molecular Mechanisms In The Lifecycle Of The Plasmodium Parasitedespite Research Efforts Over The Years, Malaria Remains A Major Health Issue. The Complex Biology Of The Plasmodium Parasite, Transmitted By Mosquitoes, Poses Challenges In Developing New Interventions. Plasmodium Initially Travels Through The Bloodstream And Reaches The Liver Where It Undergoes A Period Of Growth And Multiplication. Funded By The European Research Council, The Passage Project Is Interested In Investigating The Molecular Mechanisms Underlying The Liver Stage Of The Parasite Life Cycle. Researchers Will Build On Recent Evidence Linking The Liver Stage With Dna Damage, Which Likely Causes Genetic Variability And May Impact Disease Severity. Investigating These Dynamics Could Yield Crucial Insights For Combating Malaria Through Targeted Interventions.
Funded Under
European Research Council (Erc)
Total Cost
€ 2 467 196,25
Eu Contribution
€ 2 467 196,25
Coordinated By
Instituto De Medicina Molecular Joao Lobo Antunes
Portugal
