📋 Tender Overview
Neuronal Control Of Fascia
Fascia Innervation And Organ Damage Controlthe Connective Tissue Fascia Is The Largest Tissue In The Body, Delineating The Skin And All Organs. The Reasons Why This Mechanical Barrier Is Populated With Immune Cells And Innervated By Sensory And Sympathetic Neurons Are Unclear. The Erc-Funded Neurofascia Project Proposes That Fascia Forms A Sensory Platform For Detecting Damage To The Tissues And Communicates Information To The Brain To Initiate Corrective Mechanisms And Immune Activity. The Preliminary Results Indicate That Chronic Depression In Mice Or Optogenetic Activation Of Sympathetic Fascia Innervations Induces Immune Changes In The Fascia. The Project Objectives Include Characterisation Of The Fascia Innervation And Resident Immune Cells, The Study Of The Manifestation Of Fascia Inflammation In The Brain, And Understanding The Neural Control Of The Fascia And Its Immune State.
Funded Under
European Research Council (Erc)
Total Cost
€ 2 000 000,00
Eu Contribution
€ 2 000 000,00
Coordinated By
Technion - Israel Institute Of Technology
Israel
