π Tender Overview
Mechano-Modulation Of Tumor Microenvironment With Mechanotherapeutics And Sonopermeation To Optimize Nano-Immunotherapy
Synergistic Strategies For Reversing Vascular Compression In Cancerin Certain Types Of Cancer, Blood Vessels Endure Compression Due To Stiffness Caused By The Intricate Interactions Between Cancer Cells And The Tumour Microenvironment. This Leads To Reduced Blood Flow, Compromising Drug Delivery And Effectiveness, As Well As Helping Cancer Cells Evade Immune Responses. Funded By The European Research Council, The Mmscancer Project Proposes To Combine Strategies That Mechanically Modulate The Tumour Microenvironment. The Synergistic Effect Of Mechanotherapeutics And Ultrasound Sonopermeation Is Expected To Improve Drug Delivery Through Impermeable Tumours. Researchers Will Employ Both Computational Modelling And Experimentation To Improve The Methodology Of These Strategies.
Funded Under
European Research Council (Erc)
Total Cost
β¬ 1 500 000,00
Eu Contribution
β¬ 1 500 000,00
Coordinated By
University Of Cyprus
Cyprus