📋 Tender Overview
Light-Induced Synthesis Of Protein-Drug Conjugates For Imaging And Therapy
Light-Activated Functionalisation Of Proteinsthe Development Of New Tools For Application In Fundamental Research And Clinical Medicine Involves The Functionalisation Of Biologically Active Proteins With A Range Of Different Cargo Molecules. The Goal Of The Eu-Funded Photopharma Project Is To Functionalise Proteins By New Photochemical Reagents That Are Activated By The Light As An Alternative To Currently Available Thermally-Mediated Coupling Chemistries. Light-Induced Activation Has The Potential To Solve Many Complications Encountered In The Synthesis Of Radiolabelled Antibodies And Other Protein-Conjugates Using Thermal Coupling. The Ultimate Project Goals Are To Enable The Synthesis And Clinical Translation Of Protein-Drug Conjugates By Introducing A Radical New Technology Based On The Fast, Reliable And Automated Approach Of Using Light-Induced Chemistry.
Funded Under
Excellent Science - European Research Council (Erc)
Total Cost
€ 2 000 000,00
Eu Contribution
€ 2 000 000,00
Coordinated By
Universitat Zurich
Switzerland
