📋 Tender Overview
Identifying The Steps Required For Meiotic Dna Double-Strand Break Formation
Molecular Insight Into Chromosomal Recombination During Meiosisthe Formation Of Dna Double Strand Breaks (Dsbs) During Meiotic Division Is Necessary For Recombination And Fertility. However, Meiotic Dsbs Pose A Major Challenge For Genomic Integrity. The Eu-Funded Dsbsunrise Project Will Investigate The Hypothesis That This Process Is Tightly Regulated To Ensure Efficient Dna Dsb Repair By Homologous Recombination. Researchers Will Provide Topological Insight Into The Process And Identify The Genomic Sites Where Dsbs Take Place. They Will Also Study How Dsb Sites Interact With Structural Components Of The Repair Mechanism, Offering Fundamental Knowledge On The Complex Process Of Meiotic Chromosomal Recombination.
Funded Under
Excellent Science - European Research Council (Erc)
Total Cost
€ 2 170 000,00
Eu Contribution
€ 2 170 000,00
Coordinated By
Centre National De La Recherche Scientifique Cnrs
France
