Central Repository Digital Tender

Grant agreement ID 945358Start date 1 February 2021End date 31 January 2027Overall budget 69 641 907ObjectiveBIGPICTURE a pathology-led consortium has the vision to become the catalyst in digital transformation in Pathology. Our mission is to create the first European GDPR compliant platform in which both quality-controlled Whole Slide Imaging WSI data and advanced Artificial intelligence AI algorithms will exist. The BIGPICTURE platform will be built on existing assets of ELIXIR EU data infrastructure including the federated European Genome-phenome Archive EGA technology for managing the exchange of confidential information between contributors and users. The consortium will use Cytomine an established open-source cross-platform framework to develop unique tools for access to WSI including annotations and visualisation of algorithm results while we will develop new and generic models to facilitate AI development and mining of WSI data. By engaging and building consensus with all the relevant stakeholders we will contribute to the development of a regulatory framework for digital slides and AI-based methods. Finally BIGPICTURE envisions sustainability of its platform through a community- based model which relies on reciprocity value creation and inclusiveness.To achieve our vision we have brought together Europes leaders in the field of computational pathology who have access to national and European high-performance computing infrastructures as well as Europes fully digitalised pathology departments. Additionally the consortium has currently access to approximately 4.5 million clinical WSI covering a wider range of indications through 17 partners and 23 third parties from the largest European and international pathology and trial groups. Our consortium is further strengthened by the presence of the European Society of Pathology Digital Pathology Association FDA and 9 SMEs as partners while we are further supported by professional societies and patient advocates.