📋 Tender Overview
Cell Plasticity In Metastatic Colorectal Cancer
Unexplored Aspects Of The Microenvironment In Colorectal Cancerthe Tumour Microenvironment (Tme) Is An Integral Part Of Tumours, With A Central Role In Disease Progression And Prognosis. The Tme Consists Of Connective Tissue And Various Non-Malignant Cells Including Fibroblasts, Immune Cells And Mesenchymal Stem Cells. The Eu-Funded Plastican Project Is Interested To Understand How The Plasticity Of Stromal Cells Influences Progression And Metastasis In Colorectal Cancer. Researchers Will Study The Mechanisms Underlying The Crosstalk Between Tumour And Stromal Cells And Delineate The Role Of Distinct Cell Types. Apart From Fundamental Knowledge In Cancer Biology, Results Have The Potential To Lead To Novel Therapeutic Strategies For Colorectal Cancer.
Funded Under
Excellent Science - European Research Council (Erc)
Total Cost
€ 2 500 000,00
Eu Contribution
€ 2 500 000,00
Coordinated By
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Stiftung
Germany
